If you're applying under the Highly Specialised Work stream, ensure your skills are not readily available in Australia, and refrain from commencing work until your visa is approved unless you already hold a valid work visa. Additionally, remember that you must be outside of Australia at the time of application and lodgement.
While you can generally include your spouse/partner and children in your visa application, they are typically not allowed to work or study in Australia, except for specific language training programs. Access to Medicare or other social security benefits is generally not available, except for citizens of certain countries with reciprocal arrangements. It's crucial to note that you cannot renew Australian visas, and applying for a further 400 visa may suggest ongoing work, leading to refusal. In such cases, a Temporary Skill Shortage (TSS) visa may be more appropriate.